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Emyria and UWA expand unique MDMA-inspired analogue library - TechInvest Magazine Online

Written by Staff Writers | Oct 19, 2022 8:39:08 AM

Clinical stage biotech firm Emyria Limited (ASX: EMD) has achieved positive progress with its preclinical MDMA-inspired drug discovery programme with partner, the University of Western Australia and led by medicinal chemistry expert, Dr Matt Piggott.

Emyria and UWA have been actively growing and screening a unique drug-discovery pipeline of novel MDMA analogues to identify new chemical entities and drug candidates with the potential to address major unmet needs in mental health and neurological disorders. Emyria previously secured exclusive rights to all MDMA-like compounds created under the partnership with Prof. Piggott and UWA.

Additional compound synthesis and screening is ongoing and a fourth batch of 14 unique compounds, inspired by previous screening results, was recently prepared and shipped for preliminary screening with Eurofins. This brings the total number of unique compounds in the library to over 140.

Five high priority compounds have been shipped to the USA for evaluation with specialist neuroscience CRO, PsychoGenics and additional metabolic studies have commenced with an Australian CRO to help determine the metabolic half-life of a priority set of compounds.

Emyria Limited is a clinical drug development and care delivery company focused on accelerating drug development and improving patient outcomes in neuroscience and mental health via:

  • Drug Development: Emyria has developed an Ultra-Pure cannabinoid platform that can support the registration of multiple proprietary dose forms. Emyria’s first dose form, EMD-RX5 is in Phase 3 trials
  • New Drug Discovery: Inspired by MDMA, Emyria is developing one of the world’s largest libraries of MDMA-like compounds with partner, the University of Western Australia.
  • Proprietary Real-World Data (RWD): Emyria gathers ethically-sourced data with patients cared for at Emyria’s own specialist clinical service (Emerald Clinics).

Emyria RWD can help support drug development and care model improvement.

https://emyria.com/