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Memphasys Celebrates Landmark Publication on RoXsta™ Diagnostic System

Written by Colin Hay | Jan 16, 2025 1:03:07 AM

Memphasys Limited (ASX: MEM) has achieved a significant milestone with the publication of a research manuscript in the prestigious journal Antioxidants. The study, titled A Comparative Analysis of the Antioxidant Profiles Generated by the RoXsta™ System for Diverse Biological Fluids, highlights the diagnostic capabilities of Memphasys’ proprietary RoXsta™ System.

This cutting-edge diagnostic system measures oxidative stress – a harmful imbalance between reactive oxygen species (ROS) and antioxidants – which is implicated in a wide range of conditions, including infertility, cardiovascular disease, and neurodegenerative disorders. The publication reinforces the scientific credibility and commercial potential of RoXsta™, positioning it as a transformative tool for healthcare and agricultural applications.

The RoXsta™ Advantage

At its core, the RoXsta™ System provides a detailed analysis of antioxidant activity, offering insights into three critical areas:

  • Neutralising free radicals, which cause cellular damage.
  • Suppressing the formation of harmful ROS.
  • Scavenging particularly damaging molecules, such as hydrogen and organic peroxides.

In clinical applications, these insights allow for precision in targeting antioxidant therapies, ensuring treatments are administered only where needed and avoiding the risks of over-supplementation.

Infertility is a particular focus, with oxidative stress in seminal plasma known to impair sperm function. RoXsta™’s ability to diagnose antioxidant deficiencies could significantly improve outcomes for male fertility treatments.

Beyond Human Health

The utility of the RoXsta™ System extends well beyond clinical diagnostics. Scoping studies indicate its potential in agriculture, where oxidative stress can impair livestock productivity. Recent trials involving cattle fertility underscore its applicability in improving reproductive outcomes.

The system’s versatility is further demonstrated by its ability to assess antioxidant levels in plant products, such as fruit juices, and even cosmetic formulations. This wide range of applications positions RoXsta™ as a solution capable of addressing challenges across multiple industries.

Scientific Validation and Commercial Impact

The recently published research, co-authored by Laureate Professor John Aitken, Memphasys’ Scientific Director, validates the system’s precision and scalability. Key findings include:

  • - Identification of human seminal plasma as a particularly rich source of antioxidants.
    - Validation of RoXsta™ as a scalable diagnostic system for point-of-care applications.
    - Demonstration of its versatility across clinical and agricultural settings.

Dr David Ali, Managing Director and CEO of Memphasys, commented on the achievement:

“This publication is a testament to RoXsta™’s transformative capabilities. Its diagnostic power not only reinforces Memphasys’ leadership in reproductive health but also positions us for broader market opportunities in livestock and clinical applications.”

                    Laureate Professor John Aitken

Strategic Development

The publication marks an important step in Memphasys’ strategy to expand its reach. The company is pursuing opportunities to apply the RoXsta™ System across:

  • Human Health Diagnostics: Revolutionising infertility treatments and oxidative stress management.
  • Agriculture: Enhancing livestock productivity and reproductive outcomes.
  • Global Markets: Scaling the system globally through academic and industry partnerships.

This innovation complements Memphasys’ broader portfolio, which includes its flagship Felix™ System for sperm separation. Together, these advancements cement Memphasys’ reputation as a pioneer in reproductive biotechnology.

Looking Ahead

Memphasys’ RoXsta™ System is poised to redefine oxidative stress diagnostics across industries. With its ability to provide rapid and precise antioxidant profiling, it addresses critical gaps in both clinical and agricultural sectors. The publication in Antioxidants not only validates its scientific merit but also underscores its commercial promise.

As Memphasys continues to explore new applications and markets for RoXsta™, stakeholders can expect further updates as the company drives its innovation agenda forward.